COMMD5 antibody

Catalog No. ABIN7112999

The Rabbit Polyclonal anti-COMMD5 antibody has been validated for WB, ELISA and IP. It is suitable to detect COMMD5 in samples from Human, Mouse and Rat.

Quick Overview for COMMD5 antibody (ABIN7112999)

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-COMMD5 Antibody

Purpose: COMMD5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: COMM domain containing 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for COMMD5

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Alternative Name: COMMD5

Background:

Synonyms: COMM domain-containing protein 5|Hypertension-related calcium-regulated gene protein (HCaRG)|COMMD5

Background: May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).

Molecular Weight: 25-28 kDa

Gene ID: 54951

UniProt: Q9GZQ3